|
KMID : 0882420080750050508
|
|
Korean Journal of Medicine
2008 Volume.75 No. 5 p.508 ~ p.514
|
|
|
Treatment of H. pylori-associated extragastric diseases
|
|
Choe Yon-Ho
|
|
|
Abstract
|
|
|
Besides H. pylori’s well-known roles in gastroduodenal diseases, some authors have proposed a link between H. pylori
and a number of extragastric diseases involving the cardiovascular, pulmonary, hepatobiliary, hematologic, and other
systems. Most of these reports are epidemiological or eradication trials. Idiopathic thrombocytopenic purpura and iron-deficiency anemia are the diseases that show the strongest link with H. pylori infection. According to American College of Gastroenterology Guideline on the Management of H. pylori Infection, unexplained iron-deficiency anemia belongs to controversial indications for diagnosis and treatment of H. pylori. Many cases relating H. pylori infection to iron-deficiency anemia have been described in the literature and H. pylori infection has emerged as a cause of refractory iron-deficiency anemia which is unresponsive to oral iron therapy. H. pylori-associated iron-deficiency anemia can be treated by H. pylori eradication. The mechanism by which H. pylori infection contributes to iron-deficiency anemia remains unclear. H. pylori-associated iron-deficiency anemia seems to develop in populations at increased risk for iron depletion. When pubescent girls, including athletes, are found to have iron-deficiency anemia refractory to iron administration, they should be evaluated for H. pylori infection.
|
|
|
KEYWORD
|
|
|
Helicobacter pylori, Extragastric manifestation, Iron-deficiency anemia, Idiopathic thrombocytopenic purpura, Treatment
|
|
|
FullTexts / Linksout information
|
|
|
|
|
Listed journal information
|
|
  
|
|